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MSM supplements for dogs have garnered significant attention in recent years, becoming a sought-after remedy for various canine health concerns, particularly those related to joint health and inflammation. In the vast world of canine supplements, choosing the best MSM product can be daunting, given the plethora of options available.

This article aims to simplify that process, providing an in-depth review of the top MSM supplements for our four-legged friends. Delving deep into quality, source, and purity, we’ll explore factors every dog parent should consider before making a choice. Furthermore, we’ll tackle some of the most pressing questions surrounding MSM supplements, from their safety and potential side effects to appropriate dosages and their efficacy in addressing canine allergies.

MSM for dogs

What Is MSM for Dogs and What Are the Benefits?

MSM (Methylsulfonylmethane) supplements for dogs are products that provide an additional source of this organic sulfur compound. MSM is naturally found in various foods, but when taken as a supplement, it can offer several potential health benefits for dogs:

  1. Joint Support: MSM has gained popularity primarily for its ability to support joint health. When combined with other joint supplements like glucosamine and chondroitin, MSM can help alleviate symptoms of osteoarthritis and other joint-related issues, promoting better joint function and reducing inflammation.
  2. Anti-inflammatory Properties: MSM can act as a natural anti-inflammatory agent, which can be beneficial for conditions beyond just joint issues, such as skin inflammations or internal problems.
  3. Pain Relief: The compound can also serve as a natural analgesic, helping to decrease pain sensations, which can be particularly beneficial for older dogs or those with chronic pain conditions.
  4. Skin and Coat Health: MSM can support the health and integrity of skin, hair, and nails due to its sulfur content, which is a key component of many structural body proteins.
  5. Allergy Relief: Some dog owners have observed reduced allergic reactions in their pets when given MSM, though more research is needed to confirm these benefits.
  6. Detoxification: MSM may assist the body in flushing out toxins and waste products, thus potentially supporting overall wellness.

MSM supplements for dogs come in various forms, including powders, capsules, chewable tablets, or as part of a joint supplement combination. If considering introducing MSM into your dog’s diet, it’s crucial to consult with a veterinarian for appropriate dosing and to ensure the product is of high quality. Always select products that are specifically designed for pets and avoid those meant for human consumption unless otherwise directed by a veterinarian.

Buyer’s Guide: What Factors to Consider When Choosing An MSM Supplement for DogsTop of Form

When choosing MSM supplements for your dog, consider the following factors to ensure the product’s safety and effectiveness:

  1. Purity: Ensure the MSM is pure and free from contaminants. Look for products labeled as “99.9% pure MSM” or similarly high percentages.
  2. Source: Some MSM supplements are derived from natural sources, while others are synthesized. Both types can be effective.
  3. Formulation: MSM can be available in various forms, including powders, capsules, chewables, and liquids. Choose the one that’s easiest for you to administer and for your dog to ingest.
  4. Complementary Ingredients: Often, MSM is combined with other joint-supporting ingredients like glucosamine, chondroitin, and hyaluronic acid. If your dog needs comprehensive joint support, consider a combined supplement.
  5. Certifications: Look for certifications or seals of approval from third-party organizations that indicate the product’s quality and purity.
  6. Brand Reputation: Choose a reputable brand known for producing high-quality supplements. Research reviews and consult with your veterinarian or other dog parents for recommendations.
  7. Dosage: Ensure the dosage is appropriate for your dog’s weight and needs. Some products might require multiple doses throughout the day, so select one that aligns with your routine.
  8. Additives and Fillers: Check the ingredient list for unnecessary additives, fillers, or potential allergens that might not be suitable for your dog.
  9. Price: While you shouldn’t necessarily opt for the cheapest option, compare prices and ensure you’re getting good value for your money.
  10. Safety: Always check for any recalls or reported adverse reactions associated with the supplement.
  11. Veterinarian’s Advice: Before introducing any supplement, consult with your veterinarian. They can provide insights based on your dog’s specific health needs and any potential interactions with other medications or supplements your dog might be taking.

Ensuring the quality, purity, and appropriateness of the MSM supplement for your dog’s specific needs is crucial. Doing thorough research and seeking professional advice can help in making an informed decision.

MSM supplements for dogs

The 9 Best MSM Supplements for Dogs

#1 – iHeartDogs Hip and Joint Supplement for Dogs

iHeartDogs Hip and Joint Supplement for Dogs
  • Advanced 8-in-1 formula
  • 200mg MSM content for enhanced joint support
  • Bacon-flavored yumminess
  • Contains 90 treat-like soft chews
  • Includes glucosamine, chondroitin, and turmeric

The iHeartDogs Hip and Joint Supplement for Dogs presents an impressive formulation, with its “8-in-1” blend spotlighting some of the most sought-after ingredients for canine joint health. Of particular note is its robust MSM content, known for its anti-inflammatory properties and ability to promote joint flexibility and relief. These chews, with their bacon flavor, are not only efficacious but also a treat for our canine friends, making administration a breeze. Combined with other powerhouse ingredients like glucosamine, chondroitin, and turmeric, this supplement represents a comprehensive approach to joint care. Over a 90-count span, it offers consistency in delivering optimal joint health benefits. For those who prioritize MSM in their pet’s joint health regimen, the iHeartDogs supplement stands out as a top choice.


  • Vet formulated with safe ingredients
  • Flavor ensures easy administration.
  • High quantity count means great value


  • Size of chews might be challenging for very small breeds
  • Potential for gastrointestinal sensitivity in some dogs

#2 – Zesty Paws Senior Advanced Glucosamine for Dogs

Zesty Paws Senior Advanced Glucosamine for Dogs
  • Specifically formulated for senior dogs
  • Enhanced with 350mg OptiMSM content
  • Includes glucosamine, chondroitin, & green-lipped mussel
  • Also formulated with turmeric Extract and Bioperine

Zesty Paws Senior Advanced Glucosamine for Dogs showcases a potent formula tailored for the unique needs of our aging furry friends. With a commendable emphasis on MSM, this supplement addresses the joint challenges senior dogs often face. Its inclusion of Glucosamine HCL, Chondroitin Sulfate, and New Zealand Green Lipped Mussel further strengthens the product’s commitment to promoting joint health and flexibility. Designed specifically with senior canines in mind, it provides a comprehensive blend that aims to make their golden years more comfortable and active. The brand’s reputation for quality is evident in this offering, and for those seeking a robust MSM presence in a senior dog supplement, Zesty Paws delivers.


  • Tempting chicken flavor
  • Recognized brand with a reputation for quality
  • Thousands of positive reviews
  • Comprehensive formula for holistic joint health


  • Might be a bit pricier compared to generic brands
  • High potency might require adjustment time for sensitive stomachs

#3 – Nutramax Cosequin Maximum Strength Joint Health Supplement for Dogs

Nutramax Cosequin Maximum Strength Joint Health Supplement for Dogs
  • Maximum strength formula chewable tablets
  • 250mg MSM content
  • Also blended with glucosamine and chondroitin.
  • Generous count of 250 chewable tablets
  • For dogs of all sizes

Nutramax Cosequin Maximum Strength stands out as a testament to the brand’s commitment to optimal joint health in dogs. The inclusion of MSM, alongside glucosamine and chondroitin, offers a powerful trinity of ingredients known to bolster joint integrity and provide pain relief. With 250 chewable tablets, this MSM supplement for dogs ensures a consistent regimen, catering to dogs of all sizes. Its versatility and wide-reaching appeal make it a staple in many pet parents’ cabinets. When it comes to delivering on the promise of joint support with an MSM spotlight, Nutramax Cosequin is hard to surpass.


  • Veterinarian recommended supplement for dogs
  • Renowned brand with proven efficacy
  • Almost 50k reviews for an average of 4.7 stars
  • Comprehensive joint support formula in one tablet


  • Tablets might be harder to administer than soft chews
  • Some dogs might not like the flavor.
  • Given the potent formula, initial dosage monitoring is crucial

#4 – Nutramax Dasuquin with MSM Joint Health Supplement for Large Dogs

Nutramax Dasuquin with MSM Joint Health Supplement for Large Dogs
  • Specifically formulated for large dogs
  • Packed with 800mg of MSM
  • With glucosamine, chondroitin, and ASU
  • Plus Boswellia Serrata Extract and Green Tea Extract
  • Offers 150 easy-to-feed soft chews

Tailored for the big pups, Nutramax’s Dasuquin with MSM offers a unique formula to support the joint health of larger breeds. Its MSM-rich composition, coupled with ingredients like glucosamine, chondroitin, ASU, and Boswellia Serrata Extract, underlines its dedication to holistic canine joint health. The inclusion of green tea extract adds a layer of antioxidant support, making it a standout in the market. With 150 soft chews designed for easy consumption, large dogs can enjoy the dual benefit of taste and joint relief. For those with sizable canines over sixty lbs., Nutramax Dasuquin with MSM emerges as a go-to choice.


  • Recommended by veterinarians
  • Recognized and trusted brand in the pet supplement industry
  • Crab-free for dogs with sensitivities
  • Easy-to-administer soft chews


  • Premium pricing due to its specialized formula
  • Some dogs might need time to adjust to the rich blend

#5 – VetriScience Laboratories GlycoFlex Plus

VetriScience Laboratories GlycoFlex Plus
  • 1000mg MSM content
  • Includes chondroitin, glucosamine, and green-lipped mussel
  • Suitable for dogs at various life stages
  • Formulated by veterinarians

VetriScience Laboratories’ GlycoFlex Plus stands out as a premier choice in canine joint health with an MSM supplement for dogs weighing over thirty pounds. At 1,000mg of MSM, these peanut butter soft chews are packed with healing power that’s clinically proven to increase hind leg strength in four weeks’ time. GlycoFlex Plus is designed to cater to medium and large dogs at different stages of life, ensuring they remain agile and pain-free. For pet parents seeking a blend of tradition and scientific innovation in joint care, GlycoFlex Plus proves to be a worthy contender.


  • Backed by VetriScience’s long-standing reputation
  • High content of active ingredients offers maximum relief
  • Made in the USA


  • Some dogs might need an acclimation period due to its potent formula
  • Priced on the higher side

#6 – PeakTails MSM Powder for Dogs

PeakTails MSM Powder for Dogs
  • 99.9% pure distilled MSM
  • 1 pounds of unflavored powder
  • Proudly made in the USA
  • Vet-owned company
  • For large dogs of all ages

PeakTails MSM Powder for Dogs stands out in its simplicity and purity. The product promises an impressive 99.9% pure distilled MSM content, ensuring pet parents provide their canines with an unadulterated boost to joint health. Packaged as a one-pound offering, the flexibility of this powder form allows for easy integration into various feeding routines. Made in the USA, its local production is a nod to quality and traceability. For those who prioritize purity and adaptability in their MSM supplement choice, PeakTails offers an unbeatable option.


  • Emphasis on purity with high MSM content
  • Flexible powder format for easy dosage adjustment
  • Easy to mix in with food
  • Trustworthiness of local USA production
  • Affordably priced


  • Requires careful storage to prevent moisture absorption
  • No additional joint-support ingredients beyond MSM

#7 – Extend Joint Care Natural Glucosamine with MSM for Dogs

Extend Joint Care Natural Glucosamine with MSM for Dogs
  • Blend of natural glucosamine and MSM
  • Focus on natural ingredients
  • Also includes type II chicken collagen and ascorbic acid
  • Delicious beef powder

Extend Joint Care offers a dual-action approach, combining the power of natural glucosamine with MSM to fortify canine joint health. This blend addresses both the structural and inflammatory aspects of joint care, providing comprehensive support. Its natural formulation ensures dogs receive a product free from unnecessary additives, leaning into nature’s best offerings for joint relief. For dog parents keen on a natural route that doesn’t compromise on the benefits of MSM, Extend Joint Care emerges as a top contender.


  • Dual-action approach for holistic joint care
  • Natural formulation assures minimal additives
  • Comes in portioned packets for easy dosing
  • Can be mixed with water to make a gravy


  • Exact MSM concentration might be unclear
  • Flavor and palatability could be an issue for some dogs

#8 – Pet Honesty Hip & Joint Health – Dog Joint Supplement Support for Dogs

Pet Honesty Hip & Joint Health - Dog Joint Supplement Support for Dogs
  • Includes glucosamine and chondroitin for added relief
  • Turmeric and Yucca Schidigera supports inflammatory response
  • Soft chew format with chicken flavor
  • No preservatives, corn, soy, GMOs, or chemical ingredients

Pet Honesty’s Hip & Joint Health supplement merges the wonders of glucosamine, chondroitin, MSM, and turmeric into a tasty chicken-flavored soft chew. The brand’s commitment to delivering a well-rounded joint health formula is evident, with MSM playing a significant role. The soft chew format ensures a treat-like experience, making the administration a pleasant process. For a comprehensive approach to joint health that combines nature’s best ingredients, Pet Honesty’s offering stands out in the crowded market.


  • Well-rounded ingredient list for holistic care
  • Treat-like experience for easy administration
  • Suitable for dogs with varying levels of joint discomfort


  • Some dogs might be sensitive to the rich blend
  • Requires consistency in administration for best results

#9 – NaturVet Methylsulfonylmethane Joint Support Dog Supplement

NaturVet MSM Joint Support Dog Supplement
  • Emphasis on MSM and sulfur-rich compounds
  • Targeted formula for cartilage, tissue, and joint support
  • Veterinarian-approved formula
  • cGMP-compliant and wheat-free

NaturVet’s MSM Joint Support Supplement zeroes in on the benefits of MSM, offering sulfur-rich compounds that play a vital role in supporting cartilage, tissue, and overall joint health. The brand’s dedication to providing a focused solution for joint concerns, particularly through the power of MSM, is commendable. The inclusion of various sulfur-rich compounds further amplifies the product’s efficacy, making it a potent choice for dog parents. For those specifically searching for an MSM-forward solution with the added benefits of sulfur compounds, NaturVet delivers.


  • Singular focus on the benefits of MSM
  • Enhanced with sulfur compounds for amplified joint support
  • Trusted brand with a history of quality products
  • Made in the USA and affordably priced


  • Lack of additional joint-support ingredients like glucosamine or chondroitin
  • Some dogs might need time to adjust to the formula

best MSM supplements for dogs

FAQs About MSM Supplements for Dogs

Is MSM safe for dogs?

MSM (Methylsulfonylmethane) is an organic sulfur compound that is naturally occurring in some plants, animals, and humans. When used in appropriate dosages, MSM is generally considered safe for dogs. It has been utilized for years in the pet industry, primarily for its anti-inflammatory properties and its ability to support joint health. However, like any supplement, the quality, source, and purity of MSM are crucial factors in ensuring its safety. It’s always wise to consult with a veterinarian before introducing MSM or any supplement to your dog’s regimen.

What are MSM side effects in dogs?

While MSM is generally well-tolerated by most dogs, there can be occasional side effects, particularly if given in high doses. Some potential side effects include gastrointestinal upset, such as diarrhea, vomiting, or reduced appetite. In some rare cases, dogs might exhibit allergic reactions or skin irritations. It’s essential to monitor your dog closely when introducing a new supplement and adjust dosages or discontinue use if any adverse effects are observed. If in doubt, it’s always best to consult with a veterinarian for guidance tailored to your pet’s specific needs.

How much MSM should I give my dog?

The appropriate dosage of MSM for your dog can vary based on several factors, including the dog’s size, weight, age, and specific health needs. Many MSM supplements formulated for dogs will provide a recommended dosage chart based on weight. As a general guideline, smaller dogs (under 20 pounds) might receive between 250-500mg per day, while larger dogs (over 100 pounds) could receive 1000-2000mg daily. However, these are rough estimates, and the specific product’s recommendations should always be followed. Furthermore, consulting with a veterinarian to determine the ideal dosage for your pet is crucial.

Can I give my dog MSM intended for human consumption?

While the chemical structure of MSM remains consistent, whether intended for humans or dogs, MSM supplements formulated for humans might contain additives, fillers, or different dosage concentrations not suitable for canine consumption. Additionally, human MSM supplements might come in forms or flavors that aren’t palatable or easy to administer to dogs. Therefore, it’s generally recommended to use MSM products specifically formulated for dogs. If considering a human MSM product for your dog, always consult with a veterinarian first to ensure its safety and appropriateness.

How long does it take to see the benefits of MSM in dogs?

The time it takes to observe the benefits of MSM in dogs can vary based on the dog’s individual health needs and the specific issues being addressed. Generally, for joint health and pain relief, many pet owners report noticing improvements within a few weeks of consistent use. However, for some dogs, noticeable changes might take longer, especially if the condition being treated is chronic or severe. It’s essential to administer the supplement consistently and be patient. For a clearer timeline specific to your dog’s condition, consulting with a veterinarian can provide more tailored insights.

Can MSM be given alongside other supplements or medications?

MSM is often found in combination with other joint health supplements like glucosamine and chondroitin, indicating its compatibility with such ingredients. In many cases, MSM can be given alongside other supplements without issue. However, if your dog is on medications, especially those with anti-inflammatory properties or those that affect blood clotting, it’s crucial to consult with a veterinarian before adding MSM to your dog’s regimen. A vet can provide guidance on any potential interactions and help ensure the combined use of MSM with other substances is safe for your dog.

Can MSM supplements help with my dog’s allergies?

Some pet parents and veterinarians have found that MSM can help reduce allergic reactions in dogs. MSM’s anti-inflammatory properties may help alleviate symptoms associated with allergies, such as skin irritations, itching, or inflammation. By reducing inflammation, MSM can potentially soothe the skin and reduce the severity of allergic reactions. However, it’s essential to note that while MSM might provide symptomatic relief, it may not address the root cause of the allergy. If you suspect your dog has allergies, consult with a veterinarian to diagnose the cause and determine the best course of action, which might include MSM as part of a broader treatment plan.

Final Thoughts

In the realm of canine care, MSM supplements for dogs have emerged as a promising tool for promoting joint health and alleviating various ailments. As pet owners, our primary goal is to ensure the utmost well-being and vitality of our furry companions. Armed with the knowledge from this review, you can confidently navigate the world of MSM supplements, making choices that best serve your dog’s unique health needs.

iHeartDogs is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no extra cost to you.

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